Draft Genome Sequence and Annotation of the Apicomplexan Parasite Besnoitia besnoiti

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Draft Genome Sequence and Annotation of the Apicomplexan Parasite Besnoitia besnoiti

The apicomplexan parasite Besnoitia besnoiti is the causative agent of bovine besnoitiosis that affects livestock, particularly cattle. The definitive host of B. besnoiti is unknown and its transmission only partially understood. Here, we report the first draft genome sequence, assembly, and annotation of this parasite.

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Neutrophil Extracellular Traps as Innate Immune Reaction against the Emerging Apicomplexan Parasite Besnoitia besnoiti

Besnoitia besnoiti infection in cattle is an important emerging protozoan disease in Europe causing economic losses and severe clinical signs, such as generalized dermatitis, orchitis, and vulvitis in affected animals. Neutrophil extracellular trap (NET) formation was recently demonstrated as an important effector mechanism of PMN acting against several invading pathogens. In the present study,...

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Ultrastructure of Besnoitia besnoiti tissue cysts and bradyzoites.

Besnoitia besnoiti is an economically important tissue cyst-forming apicomplexan of cattle in Africa and Israel. Tissue cysts and bradyzoites of B. besnoiti from the skin of a naturally infected bull were studied by transmission electron microscopy. Tissue cysts enclosed host cell and bradyzoites. Bradyzoites were 6-7.5 x 1.9-2.3 microm in size and contained organelles found in coccidian merozo...

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Chemotherapy of experimental Besnoitia besnoiti infection in rabbits.

Rabbits were infected with a bovine strain of Besnoitia besnoiti parasites derived from VERO cell cultures. Oxytetracycline, given at 30 mg/kg i.m. simultaneously with infection, prevented the development of orchitis. The controls received no treatment. All infected animals showed a transient febrile reaction. It is concluded that oxytetracycline has some therapeutic potential against Besnoitia...

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Natural Besnoitia besnoiti infections in cattle: chronology of disease progression

BACKGROUND Bovine besnoitiosis is an emerging protozoan disease in cattle. Neither vaccines nor chemotherapeutic drugs are currently available for prevention and treatment of Besnoitia besnoiti infections. Therefore the implementation of appropriate disease management strategies is of utmost importance. The aim of this longitudinal study was to complement current knowledge on the chronology of ...

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ژورنال

عنوان ژورنال: Genome Announcements

سال: 2017

ISSN: 2169-8287

DOI: 10.1128/genomea.01200-17